Brian A Lanman Selected Research

Therapeutics

2/2015	The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
9/2012	Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511.

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Brian A Lanman Research Topics

Disease

8	Neoplasms (Cancer) 01/2020 - 09/2012
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 01/2016
2	Multiple Myeloma 04/2016 - 01/2016
2	Carcinogenesis 02/2015 - 02/2015
1	Heart Failure 11/2020
1	Hypertrophy 11/2020
1	Myocardial Infarction 11/2020
1	Lymphoma (Lymphomas) 04/2016
1	Leukemia 04/2016
1	Hypersensitivity (Allergy) 02/2011

Drug/Important Bio-Agent (IBA)

4	Phosphotransferases (Kinase)IBA 01/2019 - 02/2015
2	Proteins (Proteins, Gene)FDA Link 11/2020 - 11/2019
2	proto-oncogene proteins pimIBA 02/2015 - 02/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2020
1	Peptides (Polypeptides)IBA 11/2020
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 11/2020
1	sotorasibIBA 01/2020
1	Cysteine (L-Cysteine)FDA Link 11/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	compound 17IBA 01/2016
1	Dihydrotachysterol (AT 10)IBA 02/2015
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 02/2015
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 09/2012
1	4- (2- ((6- methoxypyridin- 3- yl)amino)- 5- ((4- (methylsulfonyl)piperazin- 1- yl)methyl)pyridin- 3- yl)- 6- methyl- 1,3,5- triazin- 2- amineIBA 09/2012
1	AntigensIBA 02/2011

Therapy/Procedure

2	Therapeutics 02/2015 - 09/2012